Clostridium Difficile Toxin A+B Rapid Test

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چکیده

Clostridium Difficile Toxin A+B Rapid Test provides a procedure for a qualitative detection of Clostridium difficile toxin A (TcdA) and toxin B (TcdB) in two separate bands. A positive band of either toxin is a sign of an underlying Clostridium difficile infection (CDI), which should attract the attention of the physician. Samples used are liquid or semi-liquid human stool samples. Care must be taken when solid samples are analysed, since Clostridium difficile carriers may be asymptomatic and thus healthy. Unlike other immunoassay systems (ELISA and rapid tests) that only allow detection of TcdA and TcdB in combination and without any differentiation between the two, the Rapid C.difficile Toxin A+B test allows you to run a single assay with a single strip that differentiates between both of the toxins using two separated bands a red band below the blue control band when TcdA is present, and another red band above the control band when TcdB is in the sample. The test is based on the immunological capture of coloured microparticles during their passage along a membrane on which specific monoclonal antibodies against TcdA and TcdB have been immobilised at two separated locations.

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تاریخ انتشار 2014